OmegaGenics® SPM Active®, 60 Softgels

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OmegaGenics® SPM Active®, 60 Softgels


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SPM Active is a revolutionary nutritional product developed through advanced fractionation technology featuring standardized levels of SPMs (specialized pro-resolving mediators) found in fish oil. Designed to support the body’s natural capacity to respond to physical challenges and resolve physical stress.



What is OmegaGenics® SPM Active®?

SPM Active: Targeted support for the immune response

Since SPMs have been found to be critical for the resolution of the immune response, incorporating SPM Active to supplementation protocols represents a more targeted nutritional approach to support the resolution of the immune response and tissue health.*3 SPM Active is an exclusive, standardized SPM formula developed through advanced fractionation technology. Metagenics, in collaboration with world-renowned SPM experts, is the first to establish and set the standard for defining SPMs based on activity for use in nutraceutical products (ActiveIR). Active IR is a patent-pending technology exclusive to Metagenics that establishes a collective set of proprietary processes designed to isolate, measure, and verify the active SPMs 17-HDHA and 18-HEPE.

Who could benefit from OmegaGenics® SPM Active®?

  • People trying to slow the aging process
  • People with unhealthy diet patters, such as excess intake of low quality dietary fats and/or carbohydrates
  • Too little exercise or overexertion
  • Other physical stressors
  • Overload of environmental irritants

What helps OmegaGenics® SPM Active® work?

SPMs are structurally different from EPA and DHA ( omega-3 fatty acids). Although our body can utilize EPA and DHA and other polyunsaturated fatty acids (PUFAs) to generate SPMs, there are many enzymatic steps involved in this biological process.2 Sometimes factors such as aging, health status, or a poor diet can interfere with sufficient production of SPMs in the body from polyunsaturated fatty acids (PUFAs).

SPMs are functionally different from EPA and DHA. SPMs have unique pro-resolving properties, whereas EPA and DHA have other health benefits (such as supporting memory, healthy triglyceride and cardiovascular health). Therefore, adding SPM Active provides a more targeted and direct support for the resolution of the immune response.

About Metagenics

Metagenics was founded in 1983 on a brave new scientific concept: how the right nutrition could help people realize their best health possible by influencing what makes them unique—their genes. Back then we called it “genetic potential through nutrition.” It also makes us unique—it’s been our mission and a key differentiator ever since.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

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One Serving Contains:

Calories 5

Calories from Fat 5

Total Fat 0.5 g <1%* DV

Cholesterol <5 mg <2%* DV

Active Portion of Fractionated Marine Lipid Concentrate†250 mg ** DV

SPM content standardized to 18-hydroxy-eicosapentaenoic acid (18-HEPE) and17-hydroxy-docosahexaenoic acid (17-HDHA)

Other Ingredients: Fractionated marine lipid concentrate [(anchovy and sardine oil, and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, water, pectin, and sorbitol), and lemon oil. Contains: Fish (anchovy and sardine).

*Daily Value (DV) not established


Take two softgels once daily or as directed by your healthcare practitioner.

This product is gluten free.

Caution: Consult your healthcare practitioner if pregnant, nursing, or taking other nutritional supplements or medications. Keep out of the reach of children.

Storage: Keep tightly closed in a cool, dry place.


2 Softgels

Special Instructions